1020719-62-3

Basic information

• Product Name: 5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 )
• Synonyms: 5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 );2(1H)-Pyridinone, 5-Methyl-1-phenyl-d5-;5-Methyl-1-(phenyl-2,3,4,5,6-d5)-2(1H)-pyridinone
• CAS NO: 1020719-62-3
• Molecular Formula: C12H11NO
• Molecular Weight: 185.22184
• Product Categories: Aromatics;Isotope Labelled Compounds;Metabolites
• Mol File: 1020719-62-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 104-106°C
• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Ethanol, Ethyl Acetate, Methanol (Slightly)
• CAS DataBase Reference: 5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 )(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 )(1020719-62-3)
• EPA Substance Registry System: 5-Methyl-N-phenyl-2-1H-pyridone-d5 ( Pirfenidone-d5 )(1020719-62-3)

Safety Data

• Hazardous Substances Data: 1020719-62-3(Hazardous Substances Data)

Usage

Description

5-Methyl-N-phenyl-2-1H-pyridone-d5 (Pirfenidone-d5) is a deuterated compound used as an internal standard for the quantification of pirfenidone by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS). Pirfenidone is a pyridone derivative with antifibrotic, anti-inflammatory, and antioxidant properties, which has been utilized in the treatment of idiopathic pulmonary fibrosis.

Uses

Used in Pharmaceutical Industry:
5-Methyl-N-phenyl-2-1H-pyridone-d5 (Pirfenidone-d5) is used as an internal standard for the quantification of pirfenidone in the pharmaceutical industry. This application aids in the accurate measurement and analysis of pirfenidone levels, which is essential for its development and use in various therapeutic applications.
Used in Research and Development:
In the research and development sector, Pirfenidone-d5 serves as a valuable tool for studying the antifibrotic, anti-inflammatory, and antioxidant activities of pirfenidone. This helps researchers understand the compound's mechanisms of action and its potential applications in treating various diseases, such as idiopathic pulmonary fibrosis and non-alcoholic steatohepatitis (NASH).
Used in Quality Control and Analysis:
Pirfenidone-d5 is utilized in quality control and analysis processes to ensure the purity, potency, and consistency of pirfenidone-containing formulations. By using Pirfenidone-d5 as an internal standard, laboratories can accurately measure and compare the concentration of pirfenidone in different samples, ensuring the quality and efficacy of the final product.
Used in Drug Development and Testing:
In the drug development and testing industry, Pirfenidone-d5 is employed to study the pharmacokinetics, pharmacodynamics, and safety profile of pirfenidone. This information is crucial for the development of new drugs and the optimization of existing treatments, ultimately leading to improved patient outcomes.
Used in Toxicology Studies:
Pirfenidone-d5 is also used in toxicology studies to investigate the potential side effects and toxicities associated with pirfenidone. By understanding the compound's safety profile, researchers can develop strategies to minimize adverse effects and improve the overall safety of pirfenidone-based therapies.