1021171-88-9Relevant articles and documents
Serotype-selective, small-molecule inhibitors of the zinc endopeptidase of botulinum neurotoxin serotype A
Park, Jewn Giew,Sill, Peter C.,Makiyi, Edward F.,Garcia-Sosa, Alfonso T.,Millard, Charles B.,Schmidt, James J.,Pang, Yuan-Ping
, p. 395 - 408 (2007/10/03)
Botulinum neurotoxin serotype A (BoNTA) is one of the most toxic substances known. Currently, there is no antidote to BoNTA. Small molecules identified from high-throughput screening reportedly inhibit the endopeptidase-the zinc-bound, catalytic domain of