1021358-43-9

Basic information

• Product Name: N-(5-nitro-2-pyridyl)-3-trifluoromethylbenzamide
• Synonyms: N-(5-nitro-2-pyridyl)-3-trifluoromethylbenzamide
• CAS NO: 1021358-43-9
• Molecular Formula: C₁₃H₈F₃N₃O₃
• Molecular Weight: 311
• Mol File: 1021358-43-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(5-nitro-2-pyridyl)-3-trifluoromethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-nitro-2-pyridyl)-3-trifluoromethylbenzamide(1021358-43-9)
• EPA Substance Registry System: N-(5-nitro-2-pyridyl)-3-trifluoromethylbenzamide(1021358-43-9)

Safety Data

• Hazardous Substances Data: 1021358-43-9(Hazardous Substances Data)

Upstream product

• 4214-76-0 5-nitro-pyridin-2-ylamine 
• 2251-65-2 3-(Trifluoromethyl)benzoyl chloride 
• 4548-45-2 2-chloro-5-nitropyridine 
• 1801-10-1 3-trifluoromethylbenzamide 

Downstream Products

• 1021358-47-3 C₁₃H₁₀F₃N₃O 

Relevant articles and documents

Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide

Head group analogues of the antibacterial and antiparasitic drug nitazoxanide (NTZ) are presented. A library of 39 analogues was synthesized and assayed for their ability to suppress growth of Helicobacter pylori, Campylobacter jejuni, Clostridium difficile and inhibit NTZ target pyruvate:ferredoxin oxidoreductase (PFOR). Two head groups assayed recapitulated NTZ activity and possessed improved activity over their 2-amino-5-nitrothiazole counterparts, demonstrating that head group modification is a viable route for the synthesis of NTZ-related antibacterial analogues.