1021685-17-5Relevant articles and documents
Palladium(II)-catalyzed synthesis of the formylcarbazole alkaloids murrayaline A-C, 7-methoxymukonal, and 7-methoxy-o-methylmukonal
Hesse, Ronny,Krahl, Micha P.,Jaeger, Anne,Kataeva, Olga,Schmidt, Arndt W.,Knoelker, Hans-Joachim
, p. 4014 - 4028 (2014/07/08)
We describe the synthesis of the naturally occurring 2,7-dioxygenated formylcarbazole alkaloids 7-methoxymukonal, 7-methoxy-O-methylmukonal, and the murrayalines A-C. The carbazole framework was constructed by a Buchwald-Hartwig amination and a subsequent palladium(II)-catalyzed oxidative cyclization. We describe the synthesis of the naturally occurring 2,7-dioxygenated formylcarbazole alkaloids 7-methoxymukonal, 7-methoxy-O-methylmukonal, and the murrayalines A-C. The carbazole framework was constructed by a Buchwald-Hartwig amination and a subsequent palladium(II)-catalyzed oxidative cyclization. Copyright
FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION
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Page/Page column 33, (2010/04/03)
The invention provides methods for the treatment of cancer in a subject comprising administering a dansyl-carbazole compound.
CANCER THERAPY
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Page/Page column 29, (2008/12/05)
The present invention relates to methods of inducing expression of an epigenetically silenced gene, RASSFlA, in cells, particularly human cells, such as cancer cells. It also relates to methods of treating an individual, prophylactically or therapeutically, for cancer in which RASSFlA is epigenetically silenced.