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102184-11-2

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102184-11-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 102184-11-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,1,8 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 102184-11:
(8*1)+(7*0)+(6*2)+(5*1)+(4*8)+(3*4)+(2*1)+(1*1)=72
72 % 10 = 2
So 102184-11-2 is a valid CAS Registry Number.

102184-11-2Downstream Products

102184-11-2Relevant articles and documents

Modified Galacto- or Fuco-Clusters Exploiting the Siderophore Pathway to Inhibit the LecA- or LecB-Associated Virulence of Pseudomonas aeruginosa

Madaoui, Mimouna,Vidal, Olivier,Meyer, Albert,No?l, Mathieu,Lacroix, Jean-Marie,Vasseur, Jean-Jacques,Marra, Alberto,Morvan, Fran?ois

, p. 3433 - 3448 (2020)

Galacto- and fuco-clusters conjugated with one to three catechol or hydroxamate motifs were synthesised to target LecA and LecB lectins of Pseudomonas aeruginosa (PA) localised in the outer membrane and inside the bacterium. The resulting glycocluster–pseudosiderophore conjugates were evaluated as Trojan horses to cross the outer membrane of PA by iron transport. The data suggest that glycoclusters with catechol moieties are able to hijack the iron transport, whereas those with hydroxamates showed strong nonspecific interactions. Mono- and tricatechol galactoclusters (G1C and G3C) were evaluated as inhibitors of infection by PA in comparison with the free galactocluster (G0). All of them exhibited an inhibitory effect between 46 to 75 % at 100 μM, with a higher potency than G0. This result shows that LecA localised in the outer membrane of PA is involved in the infection mechanism.

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