1022081-30-6Relevant articles and documents
Design, synthesis and biological evaluations of a novel series of enediynes constituted with DNA cleavage, alkylating and DNA binding agents via varies spacers
Linb, Chi-Fong,Hwanga, Martin,Kuo, Yao-Haur,Wu, Ming-Jung
, p. 525 - 532 (2008/02/11)
Among the three series of complicated combinatory enediynes, 3a-d were more active than 2a-c and 4a-b, in which 3a-b showed equally inhibitory activity against the growth of Hepa59T/VGH, KB and Hela with mean IC50 values lower than 10 μg/mL. Co