1023-66-1

Basic information

• Product Name: 4-[2-(4-nitrophenyl)ethenyl]pyridine
• CAS NO: 1023-66-1
• Molecular Formula: C₁₃H₁₀N₂O₂
• Molecular Weight: 226.2307
• Mol File: 1023-66-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 365°C at 760 mmHg
• Flash Point: 174.5°C
• Density: 1.273g/cm³
• Vapor Pressure: 3.4E-05mmHg at 25°C
• Refractive Index: 1.694
• CAS DataBase Reference: 4-[2-(4-nitrophenyl)ethenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-nitrophenyl)ethenyl]pyridine(1023-66-1)
• EPA Substance Registry System: 4-[2-(4-nitrophenyl)ethenyl]pyridine(1023-66-1)

Safety Data

• Hazardous Substances Data: 1023-66-1(Hazardous Substances Data)

Upstream product

• 108-89-4 picoline 
• 555-16-8 4-nitrobenzaldehdye 
• 5097-93-8 trans-4-styrylpyride 
• 872-85-5 pyridine-4-carbaldehyde 
• 2609-49-6 diethyl p-nitrobenzylphosphonate 
• 100-43-6 4-vinylpyridine 
• 586-78-7 para-nitrophenyl bromide 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 100-52-7 benzaldehyde 
• 2767-70-6 (p-nitrobenzyl)triphenylphosphonium bromide 
• 636-98-6 p-nitrobenzene iodide 

Downstream Products

• 2735-15-1 (4-nitrophenyl)-4'-pyridylacetylene 
• 101645-12-9 trans-4-pyridine 
• 6318-70-3 4-(2-[4]pyridyl-ethyl)-aniline 
• 109219-15-0 4-(4-nitrostyryl)pyridine N-oxide 
• 101625-77-8 N-[4-((E)-2-Pyridin-4-yl-vinyl)-phenyl]-oxalamic acid ethyl ester 
• 101625-78-9 Sodium; [4-((E)-2-pyridin-4-yl-vinyl)-phenylcarbamoyl]-methanoate 
• 101676-59-9 4-(4-nitro-phenylethynyl)-pyridine-1-oxide 
• 1383439-18-6 C₁₃H₁₀N₂O₂*ClHO₄ 
• 139619-05-9 trans-4-pyridine 

Relevant articles and documents

Photophysical properties of ternary RE3+ (RE = Eu, Tb, Sm) hybrids with β-diketone functionalized linkages and 4-(4-nitrostyryl) pyridine though coordination bonding

In this paper, the organic ligands TTA and TAA are grafted onto the coupling agent to achieve the organic precursors (TTA-Si, TAA-Si) as first ligand and the organic 4-(4-nitrostyryl)pyridine (Nspy) is synthesized as the second ligand. Both of them are co

Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus

Antibiotic resistance remains a major global public health threat that requires sustained discovery of novel antibacterial agents with unexploited scaffolds. Structure-activity relationship of the first-generation aryl isonitrile compounds we synthesized led to an initial lead molecule that informed the synthesis of a second-generation of aryl isonitriles. From this new series of 20 compounds, three analogues inhibited growth of methicillin-resistant Staphylococcus aureus (MRSA) (from 1 to 4 μM) and were safe to human keratinocytes. Compound 19, with an additional isonitrile group exhibited improved activity against MRSA compared to the first-generation lead compound. This compound emerged as a candidate worthy of further investigation and further reinforced the importance of the isonitrile functionality in the compounds’ anti-MRSA activity. In a murine skin wound model, 19 significantly reduced the burden of MRSA, similar to the antibiotic fusidic acid. In summary, 19 was identified as a new lead aryl isonitrile compound effective against MRSA.

A small-molecule chemosensor for the selective detection of 2,4,6-trinitrophenol (TNP)

A pyridine-based small-molecule receptor (L) for the specific recognition of TNP was synthesised and characterised by 1H NMR, 13C NMR and FT-IR spectra, and the optical properties were studied by UV-Vis absorption and PL spectra. The