1023648-20-5

Basic information

• Product Name: 3-[3-(benzyloxy)phenylthio]-6-vinyl-1-chlorobenzene
• Synonyms: 3-[3-(benzyloxy)phenylthio]-6-vinyl-1-chlorobenzene
• CAS NO: 1023648-20-5
• Molecular Weight: 352.884
• Mol File: 1023648-20-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[3-(benzyloxy)phenylthio]-6-vinyl-1-chlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[3-(benzyloxy)phenylthio]-6-vinyl-1-chlorobenzene(1023648-20-5)
• EPA Substance Registry System: 3-[3-(benzyloxy)phenylthio]-6-vinyl-1-chlorobenzene(1023648-20-5)

Safety Data

• Hazardous Substances Data: 1023648-20-5(Hazardous Substances Data)

Upstream product

• 883718-60-3 4-[3-(benzyloxy)phenylthio]-2-chlorobenzaldehyde 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 

Downstream Products

• 1023648-22-7 2-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)-2-isopropylmalonic acid diethyl ester 
• 1023648-25-0 5-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)-2,2-dimethyl-5-nitro[1,3]dioxane 
• 1023648-23-8 2-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)-2-methoxymalonic acid dimethyl ester 
• 1023648-24-9 2-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)-2-fluoromalonic acid diethyl ester 
• 1023648-26-1 4-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}-2-(diphenylmethyleneamino)butyric acid ethyl ester 
• 676481-40-6 2-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)-2-methylmalonic acid diethyl ester 
• 1023648-21-6 2-acetamido-2-(2-{4-[3-(benzyloxy)phenylthio]-2-chlorophenyl}ethyl)malonic acid diethyl ester 

Relevant articles and documents

An efficient total synthesis of a sphingosine-1-phosphate receptor agonist KRP-203

An efficient total synthesis of the S1P1 agonist, KRP-203, is described. The key step involves the conjugate addition of diethyl acetamidomalonate to a styrene compound to give the core structure of KRP-203. Multigram quantities of the targeted KRP-203, sufficient for several biological studies, were obtained in six steps with an overall yield of 58%.