1025468-10-3

Basic information

• Product Name: 5-bromo-1,3-thiazole-4-carboxamide
• Synonyms: 5-bromo-1,3-thiazole-4-carboxamide;5-Bromothiazole-4-carboxamide
• CAS NO: 1025468-10-3
• Molecular Formula: C4H3BrN2OS
• Molecular Weight: 207.04842
• Mol File: 1025468-10-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-bromo-1,3-thiazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1,3-thiazole-4-carboxamide(1025468-10-3)
• EPA Substance Registry System: 5-bromo-1,3-thiazole-4-carboxamide(1025468-10-3)

Safety Data

• Hazardous Substances Data: 1025468-10-3(Hazardous Substances Data)

Upstream product

• 61830-23-7 ethyl 5‐bromo‐1,3‐thiazole‐4‐carboxylate 
• 103878-58-6 5-bromo-1,3-thiazole-4-carboxylic acid 

Relevant articles and documents

2-(1H-INDOLE-3-CARBONYL)-THIAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

2-(1H-lndole-3-carbonyl)-thiazole-4-carboxamide derivatives and the corresponding imidazole, oxazole and thiophene derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 27 to 32 and 59 to 219; examples 1 to 8; compounds 1-1 to 1-97; tables 1-a, 2 and 3).

HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS

This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts thereof, wherein R12 is a hydroxylated alkyl group and R9 contains a heterocyclic ring. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating atherosclerosis and preventing atherosclerotic disease events.