1025972-63-7

Basic information

• Product Name: {3-[5-cyano-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-1-yl]-propyl}-methyl-carbamic acid 1-chloro-ethyl ester
• Synonyms: {3-[5-cyano-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-1-yl]-propyl}-methyl-carbamic acid 1-chloro-ethyl ester
• CAS NO: 1025972-63-7
• Molecular Weight: 416.88
• Mol File: 1025972-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {3-[5-cyano-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-1-yl]-propyl}-methyl-carbamic acid 1-chloro-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[5-cyano-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-1-yl]-propyl}-methyl-carbamic acid 1-chloro-ethyl ester(1025972-63-7)
• EPA Substance Registry System: {3-[5-cyano-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-1-yl]-propyl}-methyl-carbamic acid 1-chloro-ethyl ester(1025972-63-7)

Safety Data

• Hazardous Substances Data: 1025972-63-7(Hazardous Substances Data)

Upstream product

• 59729-33-8 1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran-5-carbonitrile 
• 50893-53-3 carbonochloridic acid 1-chloro-ethyl ester 

Downstream Products

• 62498-67-3 rac-desmethylcitalopram 

Relevant articles and documents

Improved syntheses of N-desmethylcitalopram and N,N-didesmethylcitalopram

An improved and efficient synthesis of N-desmethylcitalopram (2) and N,N-didesmethylcitalopram (3) is presented. The method involved N-demethylation of citalopram (1) using 1-chloroethyl chloroformate to give 2 in 87% yield. Synthesis of 3 was accomplished by alkylation of 8 with 1-(3-bromopropyl)-2,2,5, 5-tetramethyl-1-aza-2,5-disilacyclopentane (9). Copyright Taylor & Francis Group, LLC.