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1026009-57-3

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1026009-57-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1026009-57-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,6,0,0 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1026009-57:
(9*1)+(8*0)+(7*2)+(6*6)+(5*0)+(4*0)+(3*9)+(2*5)+(1*7)=103
103 % 10 = 3
So 1026009-57-3 is a valid CAS Registry Number.

1026009-57-3Downstream Products

1026009-57-3Relevant articles and documents

Synthesis of Montelukast (MK-0476) metabolic oxidation products

Dufresne, Claude,Gallant, Michel,Gareau, Yves,Ruel, Rejean,Trimble, Laird,Labelle, Marc

, p. 8518 - 8525 (2007/10/03)

We report the chemical synthesis of six oxidized derivatives of MK-0476 (Montelukast, L-706631), which have been key tools in the identification of its metabolites. We have prepared three diastereoisomeric pairs of potential oxidative metabolites of MK-0476, starting from the (S)-hydroxy ester 7 in 10 and five steps, and starting from MK-0476 itself in one step. The key benzylic hydroxyl of 1 and 2 was introduced by a bromination and saponification reaction sequence. In the case of the hydroxyl of 3 and 4, the key step was the addition of a hydroxymethyl carbanion equivalent on ketone 20. The two sulfoxide 5 and 6 were prepared by a direct oxidation of MK-0476 with m-chloroperbenzoic acid.

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