1026067-78-6Relevant articles and documents
Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)
Radanyi, Christine,Le Bras, Gaelle,Messaoudi, Samir,Bouclier, Celine,Peyrat, Jean-Francois,Brion, Jean-Daniel,Marsaud, Veronique,Renoir, Jack-Michel,Alami, Mouad
, p. 2495 - 2498 (2008/09/20)
A new series of coumarin inhibitors of hsp90 lacking the noviose moiety as well as substituents on C-7 and C-8 positions of the aromatic ring was synthesised and their hsp90 inhibitory activity has been delineated: for example, their capacity to induce th