1026070-99-4

Basic information

• Product Name: 2-Methyl-benzoic acid [1-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-hydrazide
• CAS NO: 1026070-99-4
• Molecular Weight: 387.481
• Mol File: 1026070-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Methyl-benzoic acid [1-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-benzoic acid [1-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-hydrazide(1026070-99-4)
• EPA Substance Registry System: 2-Methyl-benzoic acid [1-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-phenyl}-meth-(E)-ylidene]-hydrazide(1026070-99-4)

Safety Data

• Hazardous Substances Data: 1026070-99-4(Hazardous Substances Data)

Upstream product

• 87-24-1 ethyl 2-methylbenzoate 
• 5223-06-3 5-ethyl-2-(2-hydroxyethyl)pyridine 
• 118-90-1 ortho-methylbenzoic acid 
• 144809-26-7 2-(5-ethyl-pyridin-2-yl)ethyl methanesulfonate 
• 7658-80-2 2-methylbenzohydrazide 
• 114393-97-4 4-[2-(5-ethylpyridyl)ethoxy]benzaldehyde 

Relevant articles and documents

Synthesis and?antimicrobial studies of?a?new series of?2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}-5-substituted-1,3,4-oxadiazoles

A series of novel 2-{4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}-5-substituted-1,3,4-oxadiazoles were synthesized by the oxidative cyclisation of hydrazones derived from 4-[2-(5-ethylpyridin-2-yl)ethoxy]benzaldehyde and aroylhydrazines using chloramine-T as oxidant. IR, NMR and elemental analysis characterized the newly synthesized compounds. The synthesized compounds were evaluated for their antimicrobial activity and were compared with standard drugs. The compounds demonstrated potent to weak antimicrobial activity. Out of the compounds studied, compounds 8c and 8d showed significant inhibition. Compounds 8b, 8f, 8k and 8e showed moderate activity. The minimum inhibitory concentration of the compounds was in the range of 8-26 μg ml-1 against bacteria and 8-24 μg ml-1 against fungi. The title compounds represent a novel class of potent antimicrobial agents.