1026131-44-1

Basic information

• Product Name: Acetic acid 2-ethoxy-4-thiazolidin-2-yl-phenyl ester
• CAS NO: 1026131-44-1
• Molecular Weight: 267.349
• Mol File: 1026131-44-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid 2-ethoxy-4-thiazolidin-2-yl-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid 2-ethoxy-4-thiazolidin-2-yl-phenyl ester(1026131-44-1)
• EPA Substance Registry System: Acetic acid 2-ethoxy-4-thiazolidin-2-yl-phenyl ester(1026131-44-1)

Safety Data

• Hazardous Substances Data: 1026131-44-1(Hazardous Substances Data)

Upstream product

• 121-32-4 4-hydroxy-3-ethoxybenzaldehyde 
• 72207-94-4 2-ethoxy-4-formylphenyl acetate 
• 156-57-0 2-mercaptoethylamine hydrochloride 

Downstream Products

• 1028292-84-3 Acetic acid 4-(3-benzenesulfonyl-thiazolidin-2-yl)-2-ethoxy-phenyl ester 

Relevant articles and documents

Synthesis and evaluation of novel thiazolidine derivatives as thromboxane A2 receptor antagonists

A series of 3-benzoyl or 3-phenylsulfonyl-2-substituted thiazolidine derivatives were synthesized, and evaluated for their thromboxane A2 (TXA2) receptor-antagonizing effect on (15S)-15-hydroxy-11α,9α- (epoxymethano)prosta-5(Z),13(E)-dienoic acid (U-46619)-induced aggregation of rabbit platelet-rich plasma (PRP). A simple 2-arylthiazolidine derivative, 3- benzoyl-2-(4-hydroxy-3-methoxyphenyl)thiazolidine (5a), showed mild TXA2 receptor antagonist activity. Modification of 5a led to 2-chloro-4-[3-(4- chlorophenylsulfonyl)thiazolidin-2-ylmethyl]phenoxyaretic acid (29d), which showed 10 times more potent TXA2 receptor antagonist activity than 5a.