1026187-62-1

Basic information

• Product Name: 2-azido-1-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethylamine
• Synonyms: 2-azido-1-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethylamine
• CAS NO: 1026187-62-1
• Molecular Weight: 434.316
• Mol File: 1026187-62-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-azido-1-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-azido-1-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethylamine(1026187-62-1)
• EPA Substance Registry System: 2-azido-1-[6-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethylamine(1026187-62-1)

Safety Data

• Hazardous Substances Data: 1026187-62-1(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 354538-35-5 (1R)-N-(tert-butyloxycarbonyl)-1-(N-tosyl-6-bromoindol-3-yl)-2-[(4-methylphenylsulfonyl)oxy]ethylamine 
• 354538-32-2 (1R)-1-(N-tosyl-6-bromoindol-3-yl)-1-azido-2-[(tert-butyldimethylsilyl)oxy]ethane 
• 354538-30-0 (1S)-1-(N-tosyl-6-bromoindol-3-yl)-2-[(tert-butyldimethylsilyl)oxy]-1-ethanol 
• 354538-34-4 (R)-2-azido-2-(N-tosyl-6-bromoindol-3-yl)-1-ethanol 
• 354538-26-4 (S)-1-(N-tosyl-6-bromoindol-3-yl)-1,2-ethanediol 
• 354538-27-5 6-bromo-1-tosyl-3-vinyl-1H-indole 
• 158991-81-2 6-bromo-N-(1-p-toluenesulphonyl)-indole-3-carboxaldehyde 
• 17826-04-9 6-bromo-1H-indole-3-carbaldehyde 
• 354538-36-6 (1R)-N-(tert-butyloxycarbonyl)-1-(N-tosyl-6-bromoindol-3-yl)-2-azidoethylamine 

Downstream Products

• 354538-37-7 (R)-3-(6-bromoindol-3-yl)-6-(N-tosyl-6-bromoindol-3-yl)-5,6-dihydro-2(1H)-pyrazinone 

Relevant articles and documents

Enantioselective synthesis for the (-)-antipode of the pyrazinone marine alkaloid, hamacanthin A

A short enantioselective total synthesis for the (-)-antipode of the antifungal marine alkaloid, hamacanthin A, (6R)-3,6-bis(6-bromoindol-3-yl)-5,6-dihydro-2(1H)-pyrazinone, is described. This synthesis proceeds through the coupling of 3-indolyl-αoxoacetyl chloride and 3-indolyl azidoethylamine, followed by intramolecular aza-Wittig type cyclization. A concise and useful approach for the synthesis of (1R)-1-(indol-3-yl)-2-azidoethylamine using the Sharpless asymmetric dihydroxylation reaction followed by stereospecific azidation is also presented.