1026308-88-2

Basic information

• Product Name: N-(1-cyano-1-methyl-ethyl)-4-methoxybenzamide
• Synonyms: N-(1-cyano-1-methyl-ethyl)-4-methoxybenzamide
• CAS NO: 1026308-88-2
• Molecular Weight: 218.255
• Mol File: 1026308-88-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(1-cyano-1-methyl-ethyl)-4-methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-cyano-1-methyl-ethyl)-4-methoxybenzamide(1026308-88-2)
• EPA Substance Registry System: N-(1-cyano-1-methyl-ethyl)-4-methoxybenzamide(1026308-88-2)

Safety Data

• Hazardous Substances Data: 1026308-88-2(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 19355-69-2 2-amino-2-cyanopropane 
• 50846-36-1 2-amino-2-methylpropanenitrile monohydrochloride 

Downstream Products

• 1026505-71-4 N-(2-Amino-1,1-dimethyl-ethyl)-4-methoxy-benzamide 

Relevant articles and documents

The Synthesis of Ketone-Derived Enamides by Elimination of HCN from Cyanoamides

Treatment of easily available ketone-derived cyanoamides with NaOtBu leads to enamides in a simple, scalable, and inexpensive one-step operation in good yield. Enamides not stabilized by conjugation or by inclusion in a ring can also be prepared. An E1cB mechanism consistent with all results and observations, is proposed. The Z geometry of the product enamide is highly favoured, and the regioselectivity can be directed by one′s choice of protecting group.