10264-39-8

Basic information

• Product Name: ESTER-105
• Synonyms: ESTER-105;Carbamodithioic acid, diethyl-, 2-cyanoethyl ester ;2-cyanoethyl N,N-diethylcarbamodithioate
• CAS NO: 10264-39-8
• Molecular Formula: C8H14N2S2
• Molecular Weight: 202.34016
• Product Categories: Beneficiation Reagent
• Mol File: 10264-39-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ESTER-105(CAS DataBase Reference)
• NIST Chemistry Reference: ESTER-105(10264-39-8)
• EPA Substance Registry System: ESTER-105(10264-39-8)

Safety Data

• Hazardous Substances Data: 10264-39-8(Hazardous Substances Data)

Usage

General Description

Ester-105 is a type of ester-based chemical compound widely used in industrial applications. It is commonly used as a plasticizer in the production of various plastic materials, including polyvinyl chloride (PVC) and other polymers. Ester-105 helps improve the flexibility, durability, and overall performance of these materials, making them suitable for a wide range of applications in construction, automotive, and consumer goods industries. Additionally, it is also used as a lubricant additive in automotive and industrial applications, where it helps reduce friction and wear in moving parts. Ester-105 is known for its excellent thermal and oxidative stability, making it a versatile and reliable choice for various industrial processes and products.

Upstream product

• 75-15-0 carbon disulfide 
• 109-89-7 diethylamine 
• 107-13-1 acrylonitrile 
• 148-18-5 sodium N,N-diethyldithiocarbamate 
• 392-74-5 diethyldithiocarbamate 

Downstream Products

• 5337-30-4 diethyldithiocarbamic acid 2-carbamoylethyl ester 

Relevant articles and documents

Synthesis of N,N-diethyldithiocarbamate nitrile ethyl and the chelating behaviors with metal ions

The N,N-diethyldithiocarbamate nitrile ethyl (NND) was the nonionic polar collector, and it can synthesize the NND in dimethyl sulfoxide solvent. This method can effectively reduce the reaction intensity and the coefficient of the synthetic risk. The purity of NND which we synthesized is 94.23%, and the yield is 91.06%. UV analysis shows that the characteristic absorption peak wavelength of the NND is 276 nm, and its absorbance is 0.901. Based on the interaction of NND + Mn+ (Mn+ = Fe3+, Cu2+, Zn2+, Pb2+) and the quantum chemical calculation analysis of the NND and ethyl xanthate, we can conclude that the flotation performance of NND should be better than that of ethyl xanthate.

OH-/silica-mediated one-pot synthesis of dithiocarbamates under solvent-free conditions

An efficient, versatile, and environmentally benign method for the synthesis of dithiocarbamates under solvent-free conditions is reported. The Michael addition of electron-deficient alkenes with alkyl or aryl amines and CS2 in the presence of OH-/silica in a one-pot three-component reaction protocol gave the corresponding dithiocarbamates in good to excellent yields. This method is suitable for a wide range of amines and a variety of Michael acceptors in solvent-free conditions. The results of the present work show the desired products in excellent yields. Copyright Taylor and Francis Group, LLC 2012.

Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer

The zinc-ejecting aldehyde dehydrogenase (ALDH) inhibitory drug disulfiram (DSF) was found to be a breast cancer-associated protein 2 (BCA2) inhibitor with potent antitumor activity. We herein describe our work in the synthesis and evaluation of new series of zinc-affinic molecules to explore the structural requirements for selective BCA2-inhibitory antitumor activity. An N(C - S)S - S motif was found to be required, based on selective activity in BCA2-expressing breast cancer cell lines and against recombinant BCA2 protein. Notably, the DSF analogs (3a and 3c) and dithio(peroxo)thioate compounds (5d and 5f) were found to have potent activity (submicromolar IC50) in BCA2 positive MCF-7 and T47D cells but were inactive (IC50 > 10 μM) in BCA2 negative MDA-MB-231 breast cancer cells and the normal breast epithelial cell line MCF10A. Testing in the isogenic BCA2 +ve MDA-MB-231/ER cell line restored antitumor activity for compounds that were inactive in the BCA2 -ve MDA-MB-231 cell line. In contrast, structurally related dithiocarbamates and benzisothiazolones (lacking the disulfide bond) were all inactive. Compounds 5d and 5f were additionally found to lack ALDH-inhibitory activity, suggestive of selective E3 ligase-inhibitory activity and worthy of further development.