1026476-67-4Relevant articles and documents
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers
Du Nguyen, Huy,Okada, Takuya,Kitamura, Shun,Yamaoka, Sakura,Horaguchi, Yamato,Kasanami, Yoshihito,Sekiguchi, Fumiko,Tsubota, Maho,Yoshida, Shigeru,Nishikawa, Hiroyuki,Kawabata, Atsufumi,Toyooka, Naoki
, p. 4410 - 4427 (2018/07/25)
Since 6-prenylnaringenin (6-PNG) was recently identified as a novel T-type calcium channel blocker with the IC50 value around 1 μM, a series of flavanone derivatives were designed, synthesized and subsequently evaluated for T-channel-blocking a