102649-78-5

Basic information

• Product Name: 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE
• Synonyms: 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE;SC-9;N-(6-PHENYLHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE;N-(6-PHENYLHEXYL)-5-CHLORO-1-*NAPHTHALEN ESULFONAMID;5-Chloro-N-(6-phenylhexyl)naphthalene-1-sulfonaMide
• CAS NO: 102649-78-5
• Molecular Formula: C22H24ClNO2S
• Molecular Weight: 401.95
• Product Categories: Protein Kinase Inhibitors and Activators;Activators
• Mol File: 102649-78-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 75-76°C
• Boiling Point: 577.5°Cat760mmHg
• Flash Point: 303.1°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 2.46E-13mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: −20°C
• Solubility: Acetonitrile (Slightly), Chloroform (Slightly)
• PKA: 11.25±0.50(Predicted)
• CAS DataBase Reference: 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE(102649-78-5)
• EPA Substance Registry System: 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE(102649-78-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 102649-78-5(Hazardous Substances Data)

Usage

Description

5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE is an organic compound with a chemical structure that features a naphthalene core, a sulfonamide group, and a phenylhexyl chain. It is characterized as a crystalline solid, which indicates its solid-state physical form.

Uses

Used in Pharmaceutical Industry:
5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to serve as a building block in the development of new drugs, particularly those targeting specific biological pathways.
Used in Biochemical Research:
In the field of biochemical research, 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE is used as a tool compound to study the activation of protein kinase C in a Ca2+-dependent manner. 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE provides insights into the mechanisms of cellular signaling and may contribute to the understanding of various diseases and conditions related to protein kinase C dysregulation.
Used in Chemical Synthesis:
As a crystalline solid, 5-CHLORO-N-(6-PHENYLHEXYL)-1-NAPHTHALENESULFONAMIDE can be utilized in chemical synthesis processes, where its specific properties and reactivity are harnessed to produce a variety of target molecules. This application is particularly relevant in the development of new materials and compounds for various industries, including pharmaceuticals, agrochemicals, and materials science.

Biological Activity

A potent activator of protein kinase C.

InChI:InChI=1/C22H24ClNO2S/c23-21-15-8-14-20-19(21)13-9-16-22(20)27(25,26)24-17-7-2-1-4-10-18-11-5-3-6-12-18/h3,5-6,8-9,11-16,24H,1-2,4,7,10,17H2