102657-39-6Relevant articles and documents
Synthesis and evaluation of bisbenzylidenedioxotetrahydrothiopranones as activators of endoplasmic reticulum (ER) stress signaling pathways and apoptotic cell death in acute promyelocytic leukemic cells
Tan, Kheng-Lin,Ali, Azhar,Du, Yuhong,Fu, Haian,Jin, Hai-Xiao,Chin, Tan-Min,Khan, Matiullah,Go, Mei-Lin
, p. 5904 - 5918 (2014/08/18)
Curcumin is known to trigger ER-stress induced cell death of acute promyelocytic leukemic (APL) cells by intercepting the degradation of nuclear co-repressor (N-CoR) protein which has a key role in the pathogenesis of APL. Replacing the heptadienedione mo