1026672-88-7

Basic information

• Product Name: 3-(2-Acetylamino-phenyl)-2-cyano-3-oxo-propionic acid ethyl ester
• Synonyms: 3-(2-Acetylamino-phenyl)-2-cyano-3-oxo-propionic acid ethyl ester
• CAS NO: 1026672-88-7
• Molecular Weight: 274.276
• Mol File: 1026672-88-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-Acetylamino-phenyl)-2-cyano-3-oxo-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Acetylamino-phenyl)-2-cyano-3-oxo-propionic acid ethyl ester(1026672-88-7)
• EPA Substance Registry System: 3-(2-Acetylamino-phenyl)-2-cyano-3-oxo-propionic acid ethyl ester(1026672-88-7)

Safety Data

• Hazardous Substances Data: 1026672-88-7(Hazardous Substances Data)

Upstream product

• 89-52-1 o-acetylamino-benzoic acid 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 15000-43-8 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonitrile 

Relevant articles and documents

Reactions of 2-methyl-3,1-benzoxazin-4-one with active methylene compounds: A new route to 3-substituted 4-hydroxyquinolin-2(1H)-ones

A new route to 3-substituted 4-hydroxyquinolin-2(1H)-ones, compounds of great biological importance, is described. The C-acylation of active methylene compounds 2 with the 2-methyl-3,1-benzoxazin-4-one 1, under basic conditions, leads to the formation of the new products 3-10, which have been isolated and characterized. Cyclization of the above intermediates furnishes the 3-substituted 4-hydroxyquinolin-2(1H)-ones. Spectral data and physical characteristics for all compounds are reported.