10268-79-8

Basic information

• Product Name: N-(2-aminophenyl)propanamide
• Synonyms: N-(2-aminophenyl)propanamide;AKOS BBV-009011;OTAVA-BB 1171747
• CAS NO: 10268-79-8
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.207
• Mol File: 10268-79-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-aminophenyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-aminophenyl)propanamide(10268-79-8)
• EPA Substance Registry System: N-(2-aminophenyl)propanamide(10268-79-8)

Safety Data

• Hazardous Substances Data: 10268-79-8(Hazardous Substances Data)

Upstream product

• 79-03-8 propionyl chloride 
• 95-54-5 1,2-diamino-benzene 
• 19314-20-6 N-(2-nitrophenyl)propionamide 
• 802294-64-0 propionic acid 

Downstream Products

• 1848-84-6 2-ethylbenzimidazole 
• 10268-76-5 N-(2-propionyllamino-phenyl)-propionamide 

Relevant articles and documents

Azobenzene-diamides as Photopharmacological Ligands for Insect Ryanodine Receptor

Photoresponsive ligands are powerful tool compounds for studying receptor function with spatiotemporal resolution. However, to the best of our knowledge, such a ligand is not available for the ryanodine receptor (RyR). Herein, we present a photochromic ligand (PCL) for insect RyR by decorating chlorantraniliprole (CHL) with photoswitchable azobenzene (AB). We demonstrated that one potent ligand, named ABCHL13, shows light-induced reversible trans-cis isomerization and 3.5-fold insecticidal activity decrease toward oriental armyworm (Mythimna separata) after UV-light irradiation, that is, trans-ABCH13 has higher activity than the cis-ABCH13. ABCHL13 enables optical control over intracellular Ca2+ release in dorsal unpaired median (DUM) neurons of M. separata and American cockroach (Periplaneta americana) and cardiac function of P. americana. Our results provide a first photopharmacological toolkit that is applicable to light-dependent regulation of RyR and heart beating.

Zeolites. Efficient and eco-friendly catalysts for the synthesis of benzimidazoles

A superior method of synthesis of 2-substituted benzimidazoles by means of the heterogeneous catalysis of synthetic and natural zeolites in the reaction of 1,2-diaminobenzene with acid chlorides is described. Springer-Verlag 2005.