1027036-69-6

Basic information

• Product Name: 1-benzyloxyimidazole 3-oxide
• Synonyms: 1-benzyloxyimidazole 3-oxide
• CAS NO: 1027036-69-6
• Molecular Weight: 190.202
• Mol File: 1027036-69-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyloxyimidazole 3-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyloxyimidazole 3-oxide(1027036-69-6)
• EPA Substance Registry System: 1-benzyloxyimidazole 3-oxide(1027036-69-6)

Safety Data

• Hazardous Substances Data: 1027036-69-6(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 35321-46-1 1-hydroxy-1H-imidazole-3-oxide 
• 100-39-0 benzyl bromide 

Downstream Products

• 121779-19-9 1-(benzyloxy)imidazole 
• 202211-96-9 1-Benzyloxy-1H-imidazole-2-carbaldehyde 
• 202211-98-1 1-(benzyloxy)-2-chloroimidazole 

Relevant articles and documents

Synthesis and crystal structures of non-symmetric 1,3-di(alkyloxy)imidazolium salts

A series of non-symmetric 1,3-di(alkyloxy)imidazolium salts were synthesized by stepwise alkylation of 1-hydroxyimidazole-3-oxide. The quaternary salts were subsequently functionalized by bromination in 2-position. A 2-azidoimidazolium salt and an imidazo

Synthesis of 2-Substituted 1-Hydroxyhnidazoles through Directed Lithiation

Benzylation of 3-hydroxyimidazole 1-oxide gave 3-(benzyloxy)imidazole 1-oxide, which was deoxygenated with phosphorous trichloride to produce 1-(benzyloxy)imidazole. 1-(Benzyloxy)imidazole was deprotonated selectively at C-2 by n-butyllithium. The anion formed was reacted with electrophiles to give 1-(benzyloxy)imidazoles with carbon, halogen, silicon, or sulfur substituents at the 2-position. Subsequent debenzylation afforded 2-substituted 1-hydroxyimidazoles which in turn could be deoxygenated to give 2-substituted imidazoles.