1027042-31-4 Usage
Description
8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz is a chemical intermediate derived from Efavirenz, an antiretroviral medication used to treat HIV/AIDS. It is an off-white solid with unique chemical properties that make it a valuable component in the synthesis of Efavirenz.
Uses
Used in Pharmaceutical Industry:
8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz is used as a key intermediate in the synthesis of Efavirenz, an antiretroviral drug. It plays a crucial role in the production process, contributing to the development of Efavirenz-based treatments for HIV/AIDS.
Used in Research and Development:
As a chemical intermediate, 8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz is also utilized in research and development for the discovery and improvement of new antiretroviral medications and therapies. Its unique properties allow scientists to explore its potential applications and optimize its use in the pharmaceutical field.
Check Digit Verification of cas no
The CAS Registry Mumber 1027042-31-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,7,0,4 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1027042-31:
(9*1)+(8*0)+(7*2)+(6*7)+(5*0)+(4*4)+(3*2)+(2*3)+(1*1)=94
94 % 10 = 4
So 1027042-31-4 is a valid CAS Registry Number.
1027042-31-4Relevant articles and documents
Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz
Markwalder, Jay A.,Christ, David D.,Mutlib, Abdul,Cordova, Beverly C.,Klabe, Ronald M.,Seitz, Steven P.
, p. 619 - 622 (2007/10/03)
Studies on the biotransformation of the clinically important non-nucleoside reverse transcriptase inhibitor efavirenz have shown that oxidation and secondary conjugation are important components of the processing of this molecule in vivo. We have synthesized metabolites of efavirenz to confirm their structure and to evaluate their activity as antivirals.
