1027231-68-0Relevant articles and documents
Isobenzofurans as Conformationally Constrained Miconazole Analogues with Improved Antifungal Potency
Lovey, Raymond G.,Elliott, Arthur J.,Kaminski, James J.,Loebenberg, David,Parmegiani, Raulo M.,et al.
, p. 4221 - 4229 (2007/10/02)
A series of halogen-substituted isobenzofuran analogues was synthesized, which represented conformationally constrained analogues of miconazole (1).In vitro and in vivo topical antifungal activity against both dermatophytes and Candida species varied wide