102733-43-7

Basic information

• Product Name: Propanedioic acid, [1-(4-chlorophenyl)propyl]-, diethyl ester
• CAS NO: 102733-43-7
• Molecular Formula: C16H21ClO4
• Molecular Weight: 312.793
• Mol File: 102733-43-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [1-(4-chlorophenyl)propyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [1-(4-chlorophenyl)propyl]-, diethyl ester(102733-43-7)
• EPA Substance Registry System: Propanedioic acid, [1-(4-chlorophenyl)propyl]-, diethyl ester(102733-43-7)

Safety Data

• Hazardous Substances Data: 102733-43-7(Hazardous Substances Data)

Upstream product

• 2940-56-9 1-bromo-1-p-chlorophenylpropane 
• 105-53-3 diethyl malonate 
• 74-84-0 ethane 
• 6827-40-3 diethyl 4-chlorobenzylidenemalonate 
• 6285-05-8 4'-chloropropiophenone 
• 104-88-1 4-chlorobenzaldehyde 
• 925-90-6 ethylmagnesium bromide 
• 996-82-7 sodium diethylmalonate 

Downstream Products

• 111654-22-9 3-phenoxybenzyl 3-ethyl-3-p-chlorophenylpropionate 
• 111654-19-4 ethyl 3-ethyl-3-p-chlorophenyl-propionate 
• 82756-60-3 1-(4-Chlorphenyl)-propylmalonsaeure 
• 57960-08-4 β-(4-Chlorphenyl)valeriansaeure 

Relevant articles and documents

Microtubing-Reactor-Assisted Aliphatic C?H Functionalization with HCl as a Hydrogen-Atom-Transfer Catalyst Precursor in Conjunction with an Organic Photoredox Catalyst

Chlorine radical, which is classically generated by the homolysis of Cl2 under UV irradiation, can abstract a hydrogen atom from an unactivated C(sp3)?H bond. We herein demonstrate the use of HCl as an effective hydrogen-atom-transfer catalyst precursor activated by an organic acridinium photoredox catalyst under visible-light irradiation for C?H alkylation and allylation. The key to success relied on the utilization of microtubing reactors to maintain the volatile HCl catalyst. This photomediated chlorine-based C?H activation protocol is effective for a variety of unactivated C(sp3)?H bond patterns, even with primary C(sp3)?H bonds, as in ethane. The merit of this strategy is illustrated by rapid access to several pharmaceutical drugs from abundant unfunctionalized alkane feedstocks.

Synthesis and fibrinolytic activity of β arylaliphatic acids. Quantitative relationships between structure and biological activity

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