1027671-54-0

Basic information

• Product Name: tert-butyl 4-(3-bromophenyl)sulfanylpiperidine-1-carboxylate
• Synonyms: tert-butyl 4-(3-bromophenyl)sulfanylpiperidine-1-carboxylate
• CAS NO: 1027671-54-0
• Molecular Weight: 372.326
• Mol File: 1027671-54-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(3-bromophenyl)sulfanylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(3-bromophenyl)sulfanylpiperidine-1-carboxylate(1027671-54-0)
• EPA Substance Registry System: tert-butyl 4-(3-bromophenyl)sulfanylpiperidine-1-carboxylate(1027671-54-0)

Safety Data

• Hazardous Substances Data: 1027671-54-0(Hazardous Substances Data)

Upstream product

• 6320-01-0 3-Bromothiophenol 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 

Downstream Products

• 887591-23-3 4-(3-bromo-benzenesulfonyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1026677-74-6 4-(3-bromo-benzenesulfonyl)-piperidine 
• 285995-09-7 4-(3-Bromophenylsulphonyl)-1-[2-(2,4-difluorophenyl)ethyl]piperidine 
• 285995-10-0 N-(2,4-difluorophenethyl)-4-(3-(carbomethoxy)phenylsulfonyl)piperidine 

Relevant articles and documents

IN VIVO ENGINEERED CEREBLON PROTEIN

Disclosed herein are in vivo engineered cereblon protein and methods of making the same. The in vivo engineered cereblon protein can include a site-specific non-naturally occurring modification at cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO: 2 or 3, the modification comprising a moiety resulting from an in vivo Michael addition reaction between an exogenous Michael acceptor and the cysteine 287 as set forth in SEQ ID NO:1, or cysteine 286 as set forth in SEQ ID NO: 2 or 3.