1028126-84-2

Basic information

• Product Name: C₁₂H₁₃N₃O₈
• Synonyms: C₁₂H₁₃N₃O₈
• CAS NO: 1028126-84-2
• Molecular Weight: 327.251
• Mol File: 1028126-84-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₃N₃O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₃N₃O₈(1028126-84-2)
• EPA Substance Registry System: C₁₂H₁₃N₃O₈(1028126-84-2)

Safety Data

• Hazardous Substances Data: 1028126-84-2(Hazardous Substances Data)

Upstream product

• 59-06-3 methyl 4-acetamido-2-ethoxybenzoate 

Downstream Products

• 1028126-85-3 C₁₂H₁₇N₃O₄ 

Relevant articles and documents

Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors

A series of hydrophobic p-aminosalicylic acid derivatives containing a lipophilic side chain at C-2 and an amino or guanidine at C-5 were synthesized and evaluated for their ability to inhibit neuraminidase (NA) of influenza A virus (H3N2). All compounds were synthesized in good yields starting from commercially available p-aminosalicylic acid (PAS) using a suitable synthetic strategy. These compounds showed potent inhibitory activity against influenza A NA. Within this series, six compounds, 11, 12, 13e, 16e, 17c, and 18e, have the good potency (IC50 = 0.032-0.049 μM), which are compared to Oseltamivir (IC50 = 0.021 μM) and could be used as lead compounds in the future.