1028432-04-3

Basic information

• Product Name: O-(tert-ButyldiMethylsilyl)-N-tosylhydroxylaMine
• Synonyms: O-(tert-ButyldiMethylsilyl)-N-tosylhydroxylaMine;TsNHOTBDMS;TsNHOTBS;N-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-4-methylbenzenesulfonamide;N-(TERT-BUTYLDIMETHYLSILYLOXY)-4-METHYLBENZENESULFONAMIDE
• CAS NO: 1028432-04-3
• Molecular Formula: C₁₃H₂₃NO₃SSi
• Molecular Weight: 301.47712
• Mol File: 1028432-04-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 90-96°C
• Boiling Point: 352.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.072±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.54±0.40(Predicted)
• CAS DataBase Reference: O-(tert-ButyldiMethylsilyl)-N-tosylhydroxylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: O-(tert-ButyldiMethylsilyl)-N-tosylhydroxylaMine(1028432-04-3)
• EPA Substance Registry System: O-(tert-ButyldiMethylsilyl)-N-tosylhydroxylaMine(1028432-04-3)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3259PSN1 8 / PGII
• WGK Germany: 2
• Hazardous Substances Data: 1028432-04-3(Hazardous Substances Data)

Upstream product

• 41879-39-4 O-(tert-butyldimethylsilanyl)hydroxylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1593-60-8 p-toluenesulfonylhydroxylamine 

Downstream Products

• 1028432-17-8 C₃₀H₄₇NO₅SSi 
• 1028432-11-2 C₂₀H₂₈N₂O₅SSi 
• 1028432-15-6 C₂₂H₃₉NO₃SSi 
• 1028432-13-4 C₁₉H₂₉NO₃SSi 
• 1028432-06-5 C₂₃H₃₅NO₃SSi 
• 1028432-05-4 C₂₂H₃₃NO₃SSi 
• 1028432-18-9 C₂₄H₃₇NO₃SSi 
• 1028432-08-7 C₂₆H₄₁NO₃SSeSi 
• 1028432-07-6 C₁₉H₃₃NO₄SSi 
• 1028432-10-1 C₂₁H₃₁NO₄SSi 
• 1028432-12-3 C₂₂H₃₁NO₃SSi 
• 1028432-09-8 C₂₅H₄₁NO₈SSi 
• 1147336-09-1 3-((N-(t-butyldimethylsilyloxy)-4-methylphenylsulfonamido)methyl)-4-thien-2-oyl-furoxan 
• 1142935-23-6 5'-deoxy-5'-[N-(tert-butyldimethylsilyloxy)-N-(p-toluenesulfonyl)amino]-2',3'-O-(isopropylidene)adenosine 

Relevant articles and documents

Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides

Aza-Heck cyclizations initiated by oxidative addition of Pd0-catalysts into the N?O bond of N-(pentafluoro-benzoyloxy)sulfonamides are described. These studies, which encompass only the second class of aza-Heck reaction developed to date, provide direct access to diverse N-heterocyclic ring systems.

O-TBS-N-tosylhydroxylamine: A reagent for facile conversion of alcohols to oximes

(Chemical Equation Presented) A variety of oximes were synthesized from the corresponding alcohols, alkyl halides, or alkyl sulfonates without using external oxidants. With this simple two-step procedure involving substitution with readily available TsNHOTBS and subsequent treatment with CsF, a range of oximes were prepared including the ones hardly preparable with conventional procedures.