10293-60-4Relevant articles and documents
Glycosylation in flow: effect of the flow rate and type of the mixer
Myachin,Orlova,Kononov
, p. 2126 - 2129 (2019)
The influence of the flow rate and the mode of mixing of reagent solutions on the result of glycosylation of isopropyl alcohol with glycooxazoline in 1,2-dichloroethane in the presence of (±)-camphor-10-sulfonic acid was studied. No reaction products were observed at low flow rates (?0.043 mL h?1) when using two Comet X-01 micromixers. Under these conditions, the disaggregation of supramers of the reagents is apparently inefficient for the reaction between them to occur. However, when one of the Comet X-01 micromixers was replaced with a T-shaped adapter (at the same flow rate), the expected reaction products, glycoside and glycal, appeared in the reaction mixture. This apparently suggests a higher disaggregation of the supramers reagents under these conditions, which allows the chemical reaction between them to occur.
Elimination reactions of glycosyl selenoxides
Chambers, David J.,Evans, Graham R.,Fairbanks, Antony J.
, p. 8411 - 8419 (2007/10/03)
Glycosyl selenoxides, generated in situ from selenoglycosides by a Sharpless-type oxidation, undergo facile syn elimination leading to 2-hydroxy and 2-amino glycals in high yield. Graphical abstract.