102949-21-3

Basic information

• Product Name: Acridine, 9,10-dihydro-9-phenyl-10-(phenylmethyl)-
• CAS NO: 102949-21-3
• Molecular Formula: C26H21N
• Molecular Weight: 347.459
• Mol File: 102949-21-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acridine, 9,10-dihydro-9-phenyl-10-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acridine, 9,10-dihydro-9-phenyl-10-(phenylmethyl)-(102949-21-3)
• EPA Substance Registry System: Acridine, 9,10-dihydro-9-phenyl-10-(phenylmethyl)-(102949-21-3)

Safety Data

• Hazardous Substances Data: 102949-21-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 260-94-6 acridine 
• 100-59-4 phenylmagnesium chloride 
• 65674-20-6 10-benzylacridin-10-ium bromide 
• 591-51-5 phenyllithium 
• 10537-12-9 9-phenyl-9,10-dihydroacridine 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Discovery of 9,10-dihydroacridines as novel class of ABCB1 inhibitors

Nonplanar 9,10-dihydroacridines were synthesized as promising C2 symmetric molecular scaffolds as inhibitors of the transmembrane efflux pump ABCB1. Within the series structure-activity relationships are discussed revealing the importance of hydrogen bond acceptor functions. A selectivity of ABCB1 inhibition is demonstrated for selected candidates and a bioanalytical study proved nontoxicity as well as missing ABCB1 substrate properties. The results encourage to further develop the promising class of ABCB1 inhibitors.