103-12-8 Usage
General Description
Sulfamidochrysoidine, also known as Sulfamidochrysoidine hydrochloride or Sulfachrysoidine hydrochloride, is a synthetic organic dye that belongs to the class of sulfonamide dyes and was historically used in the textile industry to impart a bright red-orange color to fabrics.
Description
p-[(2,4-diaminophenyl)azo]benzenesulphonamide, also known as Prontosil, is a diphenyldiazene compound with two amino substituents at the 2and 4-positions and an aminosulphonyl substituent at the 4'-position. It is recognized as the first antibacterial drug, introduced in 1935, and belongs to the class of sulfonamide antibiotics.
Uses
Used in Pharmaceutical Industry:
p-[(2,4-diaminophenyl)azo]benzenesulphonamide is used as an antibacterial agent for its ability to inhibit bacterial growth and treat infections caused by susceptible bacteria. Its historical significance as the first sulfonamide antibiotic has paved the way for the development of a wide range of antibiotics that have revolutionized the treatment of bacterial infections.
Used in Research and Development:
In addition to its clinical applications, p-[(2,4-diaminophenyl)azo]benzenesulphonamide is also used as a research tool in the development of new antibiotics and the study of bacterial resistance mechanisms. Its unique chemical structure and properties make it a valuable compound for understanding the interactions between antibiotics and bacterial cells, which can contribute to the design of more effective and targeted treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 103-12-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 103-12:
(5*1)+(4*0)+(3*3)+(2*1)+(1*2)=18
18 % 10 = 8
So 103-12-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N5O2S/c13-8-1-6-12(11(14)7-8)17-16-9-2-4-10(5-3-9)20(15,18)19/h1-7H,13-14H2,(H2,15,18,19)/b17-16+
103-12-8Relevant articles and documents
Synthesis of a novel class of chromophoric cross-linkers
Haghbeen, Kamahldin,Legge, Raymond L.
, p. 957 - 965 (2016)
Considering the special place of aromatic diazo compounds in photo-responsive materials and growing demand for materials with interesting optical properties, a new class of chromophoric cross-linkers was synthesized by acrylation of diazo derivatives of m-diaminobenzene. The cross-linkers are soluble in a wide variety of organic solvents as well as in mixtures of water and water miscible solvents. The chromophores of the cross-linkers are stable in protic and some certain aprotic solvents and remain stable after cross-linking. The chemical structure of this class allows one to have a cross-linker with tuned chemical reactivity and solubility with post-linking applicability. The cross-linkers are obtained from reactions with simple chemistry in high yields and are able to participate in radical and ionic polymerization as well as in nucleophilic addition reactions. Successful participation of these substances in acrylamide polymerization and sol-gel preparation is demonstrated.
