103-34-4Relevant articles and documents
A new method for the synthesis of N,N′-thiobisamines
Dudin
, p. 1796 - 1797 (1997)
Reaction of secondary amines (morpholine and piperidine) with sulfur and iodine afforded N,N′-thiobisamines in good yields.
Method for synthesizing 4,4'-dithiodimorpholine
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Paragraph 0017-0024, (2019/10/23)
The invention discloses a method for synthesizing 4,4'-dithiodimorpholine. Sulfur monochloride and morpholine are used as raw materials, anhydrous trisodium phosphate is used as an acid binding agent,the sulfur monochloride and morpholine are reacted to produce 4,4'-dithiodimorpholine and hydrochloric acid, and the anhydrous trisodium phosphate can react with the hydrochloric acid generated in the reaction to avoid the hydrochloric acid with from reacting morpholine and the morpholine from losing the reactivity. The acid binding agent anhydrous trisodium phosphate is added in the method of the invention, so the dosage of the raw material morpholine is reduced, and the production cost is saved; and the product and impurities can be separated by washing with water after the reaction is finished, so the method has the advantages of simple production, high operability, simplicity in post-treatment and industrial application values. The appearance of the obtained product is a white needlecrystal, the yield is 90% or above, the purity is 98% or above, and use requirements are met.
Design, synthesis, and insecticidal activities of new N-benzoyl-N'-phenyl- N'-sulfenylureas
Sun, Ranfeng,Zhang, Yonglin,Chen, Li,Li, Yongqiang,Li, Qingshan,Song, Haibin,Huang, Runqiu,Bi, Fuchun,Wang, Qingmin
experimental part, p. 3661 - 3668 (2010/06/19)
Aseries of new N'-alkylaminothio,N'-arylaminothio (or dithio), and N',N'-thio (or dithio) derivatives ofN'-benzoyl-N'-phenylureas were designed and synthesized as insect-growth regulators with sulfur dichloride or disulfur dichloride as the original reactant. The new compounds were identified by 1H nuclear magnetic resonancee (NMR) spectroscopy, elemental analysis [or high-resolution mass spectrometry (HRMS)], and single-crystal X-ray diffraction analysis. The X-ray results demonstrated that there exist N-S-N or N-S-S-N bonds in these new compounds. In comparison to the parent N-benzoyl-N'-phenylureas, these derivatives displayed better solubility. The insecticidal activities of the target compounds were evaluated. The results of bioassays showed that compounds 1-24 retained the larvicidal activities of the corresponding benzoylphenylureas (BPUs) and some compounds exhibited better larvicidal activities against oriental armyworm and mosquitoes than the parent BPUs. The larvicidal activities of the selected target compounds 1 and 24 against diamondback moth were better than that of the corresponding parent compounds E and triflumuron.