103085-53-6

Basic information

• Product Name: 8-(1,2-dihydroxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one
• Synonyms: 8-(1,2-dihydroxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one
• CAS NO: 103085-53-6
• Molecular Weight: 310.35
• Mol File: 103085-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(1,2-dihydroxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(1,2-dihydroxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one(103085-53-6)
• EPA Substance Registry System: 8-(1,2-dihydroxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one(103085-53-6)

Safety Data

• Hazardous Substances Data: 103085-53-6(Hazardous Substances Data)

Upstream product

• 3468-00-6 3-methyl-2-phenyl-8-(1-propenyl)-4H-1-benzopyran-4-one 
• 103085-50-3 8-(1,2-epoxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one 

Downstream Products

• 3468-01-7 3-methylflavone-8-carboxylic acid 
• 103085-54-7 8-formyl-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran 

Relevant articles and documents

Electrochemical Epoxidation and Carbon-Carbon Bond Cleavage for the Preparation of 3-Methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic Acid from 3-Methyl-2-phenyl-8-(1-propenyl)-4H-1-benzopyran-4-one

Electrooxidative carbon-carbon bond cleavage is useful for the preparation of 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylic acid (1b) from 3-methyl-2-phenyl-8-(1-propenyl)-4H-benzopyran-4-one (2).Olefin 2 was transformed into 3-methyl-8-(1,2-epoxypropyl)-3-methyl-2-phenyl-4H-1-benzopyran-4-one (3) by the electrochemical bromohydrination in an MeCN-H2O-H2SO4-NaBr-(Pt) system followed by treatment of aqueous sodium hydroxide (94percent).The epoxide 3 was electrooxidized in an MeOH-H2SO4-(C) system, affording 8-formyl-3-methyl-2-phenyl-4H-1-benzopyran-4-one (4) in 83percent yield.Hydrogen peroxide oxidation of 4 in refluxing 2-butanone gave 1b in 86percent yield.