103108-15-2

Basic information

• Product Name: syn-ethyl 4-cyclohexyl-3-hydroxydithiopentanoate
• CAS NO: 103108-15-2
• Molecular Weight: 260.465
• Mol File: 103108-15-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: syn-ethyl 4-cyclohexyl-3-hydroxydithiopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: syn-ethyl 4-cyclohexyl-3-hydroxydithiopentanoate(103108-15-2)
• EPA Substance Registry System: syn-ethyl 4-cyclohexyl-3-hydroxydithiopentanoate(103108-15-2)

Safety Data

• Hazardous Substances Data: 103108-15-2(Hazardous Substances Data)

Upstream product

• 870-73-5 ethyl dithioacetate 
• 2109-22-0 (2-cyclohexylpropanal) 

Relevant articles and documents

DIASTEREOFACIAL SELECTIVITY VIA ALDOL REACTIONS USING ETHYL DITHIOACETATE AND ETHYL DITHIOPROPIONATE ENOLATES

The lithium enolate of ethyl dithioacetate reacts with α-methyl aldehydes to yield the aldol products in which the syn configuration in the positions β and γ to the thiocarbonyl of the product is favored over the anti configuration.This selectivity is solvent-dependent, and is enhanced at lower temperatures.In most cases, syn:anti product ratios obtained under these conditions varied from 57:43 to >99:1, depending upon the structure of the α-methyl aldehyde.When the lithium enolate of ethyl dithiopropionate was allowed to react with α-methyl aldehydes, only two out of the four possible diastereomers were detected in the product mixtures.