1031289-46-9

Basic information

• Product Name: N-[3-(trifluoromethoxy)benzyl]-1,4-dioxaspiro[4.5]decan-8-amine
• Synonyms: N-[3-(trifluoromethoxy)benzyl]-1,4-dioxaspiro[4.5]decan-8-amine
• CAS NO: 1031289-46-9
• Molecular Weight: 331.335
• Mol File: 1031289-46-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[3-(trifluoromethoxy)benzyl]-1,4-dioxaspiro[4.5]decan-8-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(trifluoromethoxy)benzyl]-1,4-dioxaspiro[4.5]decan-8-amine(1031289-46-9)
• EPA Substance Registry System: N-[3-(trifluoromethoxy)benzyl]-1,4-dioxaspiro[4.5]decan-8-amine(1031289-46-9)

Safety Data

• Hazardous Substances Data: 1031289-46-9(Hazardous Substances Data)

Upstream product

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 93071-75-1 1-[3-(trifluoromethoxy)phenyl]methanamine 

Downstream Products

• 1031289-55-0 4-{[3-(trifluoromethoxy)benzyl]amino}cyclohexanone 
• 1031289-49-2 N-(1,4-dioxaspiro[4.5]dec-8-yl)-1-methyl-N-[3-trifluoromethoxybenzyl]-1H-imidazole-4-carboxamide 

Relevant articles and documents

HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS

The present invention relates to a series of substituted heteroaryl amides of the Formula I, wherein HET, A, X1 -X4, and R1-R12 groups are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their use for the enhancement of cognition and the treatment of the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans.