1031337-78-6Relevant articles and documents
Imidazopyridines as VLA-4 integrin antagonists
Phillips, David J.,Davenport, Richard J.,Demaude, Thierry A.,Galleway, Fiona P.,Jones, Mark W.,Knerr, Laurent,Perry, Benjamin G.,Ratcliffe, Andrew J.
scheme or table, p. 4146 - 4149 (2009/04/07)
We describe a novel series of imidazopyridine substituted phenylalanines which are potent VLA-4 antagonists. A wide variety of substituents are tolerated as replacements for the pendant 3-pyridyl ring. A clear structure-activity relationship was identifie
BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR PHARMACEUTICAL USES
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Page/Page column 33, (2008/12/06)
The present invention concerns bicyclic and heterobicyclic derivatives of formula I, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.