10317-10-9 Usage
Description
3-Chloro-2-methyl-1-propanol is an organic compound with the chemical formula C4H9ClO. It is a colorless liquid with a chloro and hydroxyl functional group attached to a branched carbon chain. 3-Chloro-2-methyl-1-propanol is known for its reactivity and is commonly used as a reagent in various chemical reactions.
Uses
Used in Chemical Synthesis:
3-Chloro-2-methyl-1-propanol is used as a reagent for the oxidation of organoboranes with sodium percarbonate. This reaction is significant in the synthesis of various organic compounds, as it allows for the conversion of organoboranes into their corresponding alcohols or carbonyl compounds.
In the field of organic chemistry, 3-Chloro-2-methyl-1-propanol serves as a versatile intermediate for the preparation of a wide range of chemical products. Its unique structure and reactivity make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. By utilizing its chloro and hydroxyl functional groups, chemists can perform various transformations, such as nucleophilic substitution, elimination, and addition reactions, to construct complex molecular architectures.
Synthesis Reference(s)
Tetrahedron Letters, 30, p. 1483, 1989 DOI: 10.1016/S0040-4039(00)99497-8
Check Digit Verification of cas no
The CAS Registry Mumber 10317-10-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,1 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 10317-10:
(7*1)+(6*0)+(5*3)+(4*1)+(3*7)+(2*1)+(1*0)=49
49 % 10 = 9
So 10317-10-9 is a valid CAS Registry Number.
10317-10-9Relevant articles and documents
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Kabalka,G.W.,Hedgecock,H.C.
, p. 1776 - 1779 (1975)
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Primary Alcohols via Nickel Pentacarboxycyclopentadienyl Diamide Catalyzed Hydrosilylation of Terminal Epoxides
Lambert, Tristan H.,Steiniger, Keri A.
supporting information, p. 8013 - 8017 (2021/10/25)
The efficient and regioselective hydrosilylation of epoxides co-catalyzed by a pentacarboxycyclopentadienyl (PCCP) diamide nickel complex and Lewis acid is reported. This method allows for the reductive opening of terminal, monosubstituted epoxides to form unbranched, primary alcohols. A range of substrates including both terminal and nonterminal epoxides are shown to work, and a mechanistic rationale is provided. This work represents the first use of a PCCP derivative as a ligand for transition-metal catalysis.
Sodium Perborate: A Mild and Convenient Reagent for Efficiently Oxidizing Organoboranes
Kabalka, George W.,Shoup, Timothy M.,Goudgaon, Naganna M.
, p. 5930 - 5933 (2007/10/02)
Sodium perborate, a readily available and inexpensive reagent, efficiently oxidizes organoboranes.The reagent permits the oxidation of a wide variety of functionally substituted organoboranes.In nearly every instance, the product yields exceed those obtained using standard oxidation procedures.
