103289-85-6

Basic information

• Product Name: (2'S,3E)-1-benzyl-1-t-butoxycarbonylamino-3-(t-butoxycarbonylpyrrolidin-2-yl)prop-2-ene
• CAS NO: 103289-85-6
• Molecular Weight: 416.561
• Mol File: 103289-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2'S,3E)-1-benzyl-1-t-butoxycarbonylamino-3-(t-butoxycarbonylpyrrolidin-2-yl)prop-2-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (2'S,3E)-1-benzyl-1-t-butoxycarbonylamino-3-(t-butoxycarbonylpyrrolidin-2-yl)prop-2-ene(103289-85-6)
• EPA Substance Registry System: (2'S,3E)-1-benzyl-1-t-butoxycarbonylamino-3-(t-butoxycarbonylpyrrolidin-2-yl)prop-2-ene(103289-85-6)

Safety Data

• Hazardous Substances Data: 103289-85-6(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 103289-80-1 (2'S,3E)-methyl 2-benzyl-4-(1-t-butoxycarbonylpyrrolidin-2-yl)but-3-enoate 
• 103289-78-7 (S)-2-((E)-3-Methoxycarbonyl-propenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 100-39-0 benzyl bromide 
• 69610-41-9 Boc-L-Pro-H 
• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 103289-97-0 (S)-2-((E)-3-Isocyanato-4-phenyl-but-1-enyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 75-65-0 tert-butyl alcohol 
• 207915-32-0 (2'S,3E)-2-benzyl-4-(1-t-butoxycarbonylpyrrolidin-2-yl)but-3-enoic acid 
• 103289-74-3 (2'S,3E)-4-(1-t-butoxycarbonylpyrrolidin-2-yl)-1-trimethylsilylbut-3-enoic acid 
• 103289-73-2 (2'S,3E)-4-(1-t-butoxycarbonylpyrrolidin-2-yl)-1-trimethylsilylbut-3-en-1-yne 

Downstream Products

• 145149-48-0 tert-butyl 1-hydroxy-3-phenylpropan-2-ylcarbamate 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 

Relevant articles and documents

On the Double Bond Isostere of the Peptide Bond: Preparation of Modified Di- and Tri-peptides incorporating Proline and Alanine Analogues

The preparation of some analogues of representative peptides that incorporate double bond isosteres of the sequences, Pro-Gly, Pro-Leu, Pro-Phe, Ala-Gly, and Ala-Ala, are described.The method of synthesis involves selective hydroboronation and oxidation of conjugated enynes, to generate βγ-unsaturated acids, followed by selective α-alkylation in order to introduce a second substituent into the 'peptide' backbone.