103343-66-4

Basic information

• Product Name: (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE
• Synonyms: (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE;2H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-1-methyl-5-phenyl-, (3S)-
• CAS NO: 103343-66-4
• Molecular Formula: C₁₆H₁₅N₃O
• Molecular Weight: 265.3098
• Mol File: 103343-66-4.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE(103343-66-4)
• EPA Substance Registry System: (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE(103343-66-4)

Safety Data

• Hazardous Substances Data: 103343-66-4(Hazardous Substances Data)

Usage

Description

(R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE is a benzodiazepine derivative featuring a molecular structure that comprises a benzene ring and a seven-membered diazepine ring. As a chiral compound, the (R)-enantiomer is the active form. (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE is known for its potential sedative, anxiolytic, and muscle relaxant properties, which are typically associated with benzodiazepines. These properties make them useful in the treatment of anxiety, insomnia, and seizure disorders. However, the specific pharmacological effects of (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE may differ based on its stereochemistry and the presence of other molecular substituents. Further research is essential to comprehend its full therapeutic potential and safety profile.

Uses

Used in Pharmaceutical Industry:
(R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE is used as a potential therapeutic agent for the treatment of anxiety, insomnia, and seizure disorders due to its benzodiazepine nature and associated properties.
Used in Research and Development:
(R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE is also utilized in research and development settings to study its pharmacological effects, stereochemistry, and the possibility of its application in the development of new drugs with improved efficacy and safety profiles.

Upstream product

• 103421-61-0 3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 
• 108896-03-3 (R)-2-Amino-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-phenyl-propionamide 
• 103343-63-1 3(S)-(2(S)-amino-3-phenylpropanoylamino)-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 103343-63-1 (R)-α-amino-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)benzenepropanamide 
• 14439-71-5 2'-benzoyl-2-bromo-acetanilide 
• 103343-62-0 1,1-dimethylethyl<(R)-2-<(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)amino>-2-oxo-1-(phenylmethyl)ethyl>carbamate 
• 103373-62-2 1,3-dihydro-1-methyl-3-oximido-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 2898-08-0 2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 
• 3034-65-9 1-methyl-2,3-dihydro-2-oxo-5-phenyl-1,4-benzodiazepine 
• 103343-61-9 [(R)-1-(2-Oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 
• 207600-12-2 [1-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamoyl)-2-phenylethyl] carbamic acid tert-butyl ester 
• 207600-11-1 [(S)-1-(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester 
• 103343-47-1 3-amino-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one 

Downstream Products

• 103420-77-5 devazepide 
• 116842-78-5 4-Methyl-pentanoic acid ((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-amide 
• 108896-04-4 (3S)-(-)-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2-iodobenzenecarboxamide 
• 116842-94-5 N-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-4-pentyl-benzamide 
• 116842-81-0 (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-2,2-dimethylpropanamide 
• 118101-09-0 1-((S)-1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-m-tolyl-urea 
• 103421-59-6 2-Chloro-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-benzamide 
• 116842-95-6 (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-4-(trifluoromethyl)-benzamide 
• 116842-77-4 (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-2-methylpropanamide 
• 116842-80-9 (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-3-phenyl-2-propenamide 
• 103343-69-7 (S)-(-)-1,3-Dihydro-3-(4-bromobenzoylamino)-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 
• 116842-79-6 (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-cyclohexanecarboxamide 

Relevant articles and documents

Crystallization-induced asymmetric transformation: Stereospecific synthesis of a potent peripheral CCK antagonist

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