1033865-68-7

Basic information

• Product Name: 3-{[6-(cyclopropyl(ethyl)amino)pyridin-3-ylmethyl](4-fluorophenyl)carbamoyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester
• Synonyms: 3-{[6-(cyclopropyl(ethyl)amino)pyridin-3-ylmethyl](4-fluorophenyl)carbamoyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester
• CAS NO: 1033865-68-7
• Molecular Weight: 578.686
• Mol File: 1033865-68-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{[6-(cyclopropyl(ethyl)amino)pyridin-3-ylmethyl](4-fluorophenyl)carbamoyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{[6-(cyclopropyl(ethyl)amino)pyridin-3-ylmethyl](4-fluorophenyl)carbamoyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester(1033865-68-7)
• EPA Substance Registry System: 3-{[6-(cyclopropyl(ethyl)amino)pyridin-3-ylmethyl](4-fluorophenyl)carbamoyl}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester(1033865-68-7)

Safety Data

• Hazardous Substances Data: 1033865-68-7(Hazardous Substances Data)

Upstream product

• 1033619-77-0 cyclopropyl-{5-[(4-fluoro-phenylamino)-methyl]-pyridin-2-yl}-ethyl-amine 
• 82716-88-9 N-benzyloxycarbonyl-1,2,3,4-tetrahydro-3(S)-isoquinolinecarboxylic acid 

Downstream Products

• 1033864-68-4 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid [6-(cyclopropyl(ethyl)amino)pyridin-3-ylmethyl](4-fluorophenyl)amide 

Relevant articles and documents

ION CHANNEL MODULATORS

The present teachings provide compounds of Formula (I): and pharmaceutically acceptable salts, hydrates, and esters thereof, wherein Ar, R1, R2, R3, p, and X are defined herein. The present teachings also provide processes for producing said compounds and their pharmaceutically acceptable salts, hydrates and esters, and methods of treating a pathological condition or disorder, or alleviating a symptom thereof, using said compounds including their pharmaceutically acceptable salts, hydrates and esters. The compounds can be useful in modulating ion channel activity including treating a variety of conditions associated with the abnormal modulation of one or more voltage-gated calcium channels.