1035018-32-6

Basic information

• Product Name: C₂₄H₂₈N₂O₇
• Synonyms: C₂₄H₂₈N₂O₇
• CAS NO: 1035018-32-6
• Molecular Weight: 456.496
• Mol File: 1035018-32-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₈N₂O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₈N₂O₇(1035018-32-6)
• EPA Substance Registry System: C₂₄H₂₈N₂O₇(1035018-32-6)

Safety Data

• Hazardous Substances Data: 1035018-32-6(Hazardous Substances Data)

Upstream product

• 76315-01-0 N-benzyl-N-(tert-butoxycarbonyl)glycine 
• 942316-98-5 methyl (4-(2-bromoacetyl)phenyl)carbamate 
• 60677-43-2 methyl N-(4-acetylphenyl)carbamate 

Downstream Products

• 1035018-31-5 (4-{2-[(benzyl-tert-butoxycarbonyl-amino)-methyl]-1H-imidazol-4-yl}-phenyl)-carbamic acid methyl ester 

Relevant articles and documents

ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (I) or (II): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L1, R3, R4, R8a, R11 and M are as defined herein. The compounds of Formula (I) or (II) are selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.