103565-87-3

Basic information

• Product Name: N-cyclohexyl-3-nitropyridin-4-amine
• Synonyms: N-cyclohexyl-3-nitropyridin-4-amine
• CAS NO: 103565-87-3
• Molecular Formula: C₁₁H₁₅N₃O₂
• Molecular Weight: 221.26
• Mol File: 103565-87-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-cyclohexyl-3-nitropyridin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-3-nitropyridin-4-amine(103565-87-3)
• EPA Substance Registry System: N-cyclohexyl-3-nitropyridin-4-amine(103565-87-3)

Safety Data

• Hazardous Substances Data: 103565-87-3(Hazardous Substances Data)

Upstream product

• 13091-23-1 4-chloro-3-nitropyridine 
• 108-91-8 cyclohexylamine 
• 31872-62-5 4-methoxy-3-nitro-pyridine 
• 15590-90-6 3-nitro-4(1H)-pyridinone 

Downstream Products

• 75125-70-1 3-amino-4-(cyclohexylamino)pyridine 
• 247102-98-3 1-cyclohexyl-7-nitro-1,5-dihydro-imidazo[4,5-c]pyridin-4-one 
• 202808-29-5 4-Chloro-1-cyclohexyl-1H-imidazo[4,5-c]pyridine 
• 247102-90-5 1-Cyclohexyl-1,5-dihydro-imidazo[4,5-c]pyridin-4-one 

Relevant articles and documents

Practical amination of nitropyridones by silylation

A practical method for coupling nitropyridones (1) with primary amines by treatment with hexamethyldisilazane has been developed, avoiding the use of hazardous reagents such as POCl3. The activation of the pyridone by a nitro group is necessary for efficient coupling, leading to aminonitropyridines (3) in good yields. Regioisomers other than 3-nitro-4-pyridone (1) were found to be substantially less reactive but would undergo coupling with primary amines.