1035690-18-6

Basic information

• Product Name: 5-bromo-2-(3'-ethoxy-3,5-difluorobiphenyl-4-ylamino)nicotinic acid
• Synonyms: 5-bromo-2-(3'-ethoxy-3,5-difluorobiphenyl-4-ylamino)nicotinic acid
• CAS NO: 1035690-18-6
• Molecular Weight: 449.252
• Mol File: 1035690-18-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-(3'-ethoxy-3,5-difluorobiphenyl-4-ylamino)nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-(3'-ethoxy-3,5-difluorobiphenyl-4-ylamino)nicotinic acid(1035690-18-6)
• EPA Substance Registry System: 5-bromo-2-(3'-ethoxy-3,5-difluorobiphenyl-4-ylamino)nicotinic acid(1035690-18-6)

Safety Data

• Hazardous Substances Data: 1035690-18-6(Hazardous Substances Data)

Upstream product

• 1035689-99-6 2-(4-bromo-2,6-difluorophenylamino)nicotinic acid 
• 29241-65-4 5-bromo-2-chloronicotinic acid 

Relevant articles and documents

AMINO NICOTINIC AND ISONICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS

A compound of formula (I) wherein : - one of the groups G1represents a nitrogen atom or a group CRc and the other represents a group CRc; - G2 represents a nitrogen atom or a group CRd; - R1 represents a group selected from hydrogen atoms, halogen atoms, C1-4 alkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C3-8 cycloalkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups; - R2 represents a group selected from hydrogen atoms, halogen atoms, hydroxyl groups, C1-4 alkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, C1-4 alkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C3-8 cycloalkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups; - Ra, Rb and Rc independently represent groups selected from hydrogen atoms, halogen atoms, C1-4 alkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C1-4alkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups; - Rd represents a group selected from hydrogen atoms, halogen atoms, hydroxyl groups, C1-4 alkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C1-4 alkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C3-8 cycloalkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups; - one of the groups G3 and G4 is a nitrogen atom and the other is a CH group; - M is a hydrogen atom or an pharmaceutically acceptable cation with the proviso that, when at least one of the groups Ra and Rb represent a hydrogen atom and G2 is a group CRd, then Rd represents a groups selected from C1-4 alkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, C3-8 cycloalkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups; and the pharmaceutically acceptable salts and N-oxides thereof.