1035690-24-4

Basic information

• Product Name: 2-(3-Cydopropoxy-phenyl)-4,4,5,5-tetraMethy-[1,3,2]dioxaborolane
• Synonyms: 2-(3-Cydopropoxy-phenyl)-4,4,5,5-tetraMethy-[1,3,2]dioxaborolane;2-(3-Cyclopropoxyphenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;3-Cyclopropoxyphenylboronic acid pinacol ester
• CAS NO: 1035690-24-4
• Molecular Formula: C₁₅H₂₁BO₃
• Molecular Weight: 260.13644
• Mol File: 1035690-24-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-(3-Cydopropoxy-phenyl)-4,4,5,5-tetraMethy-[1,3,2]dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Cydopropoxy-phenyl)-4,4,5,5-tetraMethy-[1,3,2]dioxaborolane(1035690-24-4)
• EPA Substance Registry System: 2-(3-Cydopropoxy-phenyl)-4,4,5,5-tetraMethy-[1,3,2]dioxaborolane(1035690-24-4)

Safety Data

• Hazardous Substances Data: 1035690-24-4(Hazardous Substances Data)

Usage

General Description

2-(3-Cyclopropoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane is a chemical compound with the molecular formula C13H19BO2. It is a boronic ester that is commonly used as a reagent in organic synthesis, particularly in the field of pharmaceuticals. 2-(3-Cydopropoxy-phenyl)-4,4,5,5-tetraMethy-[1,3,2]dioxaborolane is known for its ability to form stable boronate complexes with diols and other nucleophiles, making it useful in the formation of carbon-carbon and carbon-heteroatom bonds. It is also utilized in the synthesis of complex natural products and as a tool in medicinal chemistry research. Additionally, the unique structure of this compound makes it a versatile intermediate in the preparation of various functionalized materials.

Upstream product

• 1035690-22-2 1-bromo-3-(cyclopropyloxy)benzene 
• 73183-34-3 bis(pinacol)diborane 
• 591-20-8 3-Bromophenol 

Downstream Products

• 1142227-97-1 methyl 3'-(cyclopropyloxy)-2-(2,2-dimethylcyclopentyI)-1,1'-biphenyl-4-carboxylate 
• 1142227-99-3 (3'-(cyclopropyloxy)-2-(2,2-dimethylcyclopentyI)-1,1'-biphenyl-4-yl)methanol 

Relevant articles and documents

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

CONFORMATIONALLY CONSTRAINED CARBOXYLIC ACID DERIVATIVES USEFUL FOR TREATING METABOLIC DISORDERS

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I or the general formula III: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.