1035979-44-2 Usage
Description
(4S,4aS,5aR,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(MethoxyMethylaMino)Methyl]-1,11-dioxo-2-naphthacenecarboxaMide hydrochloride is a complex organic compound with a unique molecular structure. It is characterized by its octahydro-naphthoquinone core, multiple hydroxyl and amino groups, and a methoxymethyl substituent. (4S,4aS,5aR,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(MethoxyMethylaMino)Methyl]-1,11-dioxo-2-naphthacenecarboxaMide hydrochloride exhibits a range of biological activities and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(4S,4aS,5aR,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(MethoxyMethylaMino)Methyl]-1,11-dioxo-2-naphthacenecarboxaMide hydrochloride is used as an antimicrobial agent for the treatment of bacterial infections. Its unique structure allows it to target and inhibit the growth of various pathogenic bacteria, making it a valuable addition to the arsenal of antibiotics.
Used in Oncology:
In the field of oncology, this compound is used as an antineoplastic agent for the treatment of various types of cancer. Its complex structure enables it to interact with cellular targets and disrupt essential biological processes, leading to the inhibition of tumor growth and proliferation.
Used in Drug Delivery Systems:
(4S,4aS,5aR,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(MethoxyMethylaMino)Methyl]-1,11-dioxo-2-naphthacenecarboxaMide hydrochloride can be incorporated into drug delivery systems to improve the efficacy and bioavailability of other therapeutic agents. Its versatile chemical structure allows for the development of targeted drug delivery systems, enhancing the therapeutic potential of various treatments.
Used in Chemical Research:
(4S,4aS,5aR,12aS)-4-(DiMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-[(MethoxyMethylaMino)Methyl]-1,11-dioxo-2-naphthacenecarboxaMide hydrochloride also serves as a valuable research tool in the field of organic chemistry. Its unique structure and functional groups make it an interesting subject for studies on chemical synthesis, molecular interactions, and the development of new chemical compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1035979-44-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,5,9,7 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1035979-44:
(9*1)+(8*0)+(7*3)+(6*5)+(5*9)+(4*7)+(3*9)+(2*4)+(1*4)=172
172 % 10 = 2
So 1035979-44-2 is a valid CAS Registry Number.
1035979-44-2Relevant articles and documents
METHODS OF USING (4S,4AS,5AR,12AS)-4-DIMETHYLAMINO-3,10,12,12A-TETRAHYDROXY-7-[(METHOXY(METHYL)AMINO)-METHYL]-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE
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Paragraph 0100; 0101, (2013/11/19)
A method of treating a bacterial infection, e.g., a bacterial infection with methicillin resistant Staphylococcus aureus, Helicobacter pylori, Chlamydia trachomatis, or Chlamydia pneumonia, comprising administering to a subject (4S,4aS,5aR,12aS)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide or a pharmaceutically acceptable salt thereof is disclosed. More specifically, a method of treating a bacterial infection comprising administering to a subject crystalline mono hydrochloride salt, crystalline mono mesylate salt or crystalline mono sulfate salt of (4S,4aS,5aR,12aS)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide is disclosed.
SUBSTITUTED TETRACYCLINE COMPOUNDS FOR TREATMENT OF INFLAMMATORY SKIN DISORDERS
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Page/Page column 56-57, (2008/12/07)
Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
