1036740-19-8

Basic information

• Product Name: C₁₈H₂₂N₄O
• Synonyms: C₁₈H₂₂N₄O
• CAS NO: 1036740-19-8
• Molecular Weight: 310.399
• Mol File: 1036740-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₂N₄O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₂N₄O(1036740-19-8)
• EPA Substance Registry System: C₁₈H₂₂N₄O(1036740-19-8)

Safety Data

• Hazardous Substances Data: 1036740-19-8(Hazardous Substances Data)

Upstream product

• 4410-12-2 1-benzyl-[1,4]diazepane 
• 70067-45-7 4-pyridyl isocyanate 

Relevant articles and documents

ROCK INHIBITORS AND USES THEREOF

The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are compounds that inhibit Rho - protein associated kinase function. Compounds of the invention include piperazinyl pyridines, piperazinylmethyl pyridines, piperazinyl ureas and carbamates, piperazinyl pyridines and quinoilines (including isoquinliones) as well as piperazinyl (including piperazinylmethyl) pyridines and quinolines (including isoquinolines). Compounds of the invention disrupt Rho-kinase activation and function and significantly inhibit tumor cell growth and induce tumor cell death.