103675-99-6 Usage
Description
(4-BROMOPHENYL)ACETONE OXIME, with the molecular formula C10H10BrNO and a molar mass of 234.09 g/mol, is an oxime derivative of (4-Bromophenyl)acetone. It is a yellowish crystalline chemical compound that serves as a reagent in organic synthesis and chemical reactions. (4-BROMOPHENYL)ACETONE OXIME is also used as a building block in the production of pharmaceuticals and agrochemicals, acting as a chemical intermediate in the synthesis of other organic compounds. Furthermore, it is utilized in research and development to investigate chemical and biological processes and plays a role in pharmaceutical manufacturing for the synthesis of various drugs and drug intermediates.
Uses
Used in Organic Synthesis:
(4-BROMOPHENYL)ACETONE OXIME is used as a reagent for facilitating various chemical reactions and organic synthesis processes. Its unique structure allows it to participate in a range of reactions, making it a versatile compound in the field of chemistry.
Used in Pharmaceutical and Agrochemical Production:
(4-BROMOPHENYL)ACETONE OXIME is used as a building block in the production of pharmaceuticals and agrochemicals. Its role in creating the backbone of these compounds contributes to their overall effectiveness and function.
Used in Research and Development:
In the realm of research and development, (4-BROMOPHENYL)ACETONE OXIME is used as a tool to investigate chemical and biological processes. Its properties and reactivity provide valuable insights into the behavior of similar compounds and can lead to advancements in understanding complex chemical interactions.
Used in Pharmaceutical Manufacturing:
(4-BROMOPHENYL)ACETONE OXIME is employed in the synthesis of various drugs and drug intermediates. Its presence in the manufacturing process is crucial for the development of new medications and the improvement of existing ones, ultimately contributing to advancements in healthcare and medicine.
Used in Chemical Intermediate Synthesis:
(4-BROMOPHENYL)ACETONE OXIME is used as a chemical intermediate in the synthesis of other organic compounds. Its role in creating intermediates is essential for the production of a wide range of chemical products, from pharmaceuticals to industrial chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 103675-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,6,7 and 5 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 103675-99:
(8*1)+(7*0)+(6*3)+(5*6)+(4*7)+(3*5)+(2*9)+(1*9)=126
126 % 10 = 6
So 103675-99-6 is a valid CAS Registry Number.
103675-99-6Relevant articles and documents
Copper-Catalyzed Aza-Sonogashira Cross-Coupling To Form Ynimines: Development and Application to the Synthesis of Heterocycles
Lavernhe, Rémi,Torres-Ochoa, Rubén O.,Wang, Qian,Zhu, Jieping
supporting information, p. 24028 - 24033 (2021/10/07)
Nitrogen-substituted alkynes, such as ynamines and ynamides, are versatile synthetic building blocks. Ynimines bearing additional nucleophilic and electrophilic centers relative to ynamines and ynamides are expected to have high synthetic potential. However, their chemical reactivity remains unexplored owing mainly to the lack of synthetic accessibility. We report herein a versatile copper-catalyzed synthesis of ynimines from readily available O-acetyl ketoximes and terminal alkynes. A wide range of O-acetyl ketoximes derived from diaryl ketones, aryl alkyl ketones and dialkyl ketones underwent cross-coupling with a diverse set of terminal alkynes to afford the ynimines in good to excellent yields. An unprecedented [5+1] heteroannulation reaction exploiting the reactivity of the ynimine generated in situ was subsequently developed for the synthesis of medicinally important heterocycles, including isoquinolines, azaindoles, azabenzofurans, azabenzothiophenes and carbolines.
The Palladium Assisted Transfer Reduction of α,β-Unsaturated Nitroalkenes to Oximes Using Ammonium Formate
Kabalka, George W.,Pace, R. David,Wadgaonkar, P.P.
, p. 2453 - 2458 (2007/10/02)
α,β-Unsaturated nitroalkenes are readily reduced to the corresponding oximes in good yields using ammonium formate in the presence of palladium.The reactions occur rapidly at room temperature in a solvent system of methanol and tetrahydrofuran.
A FACILE KETOXIME PREPARATION VIA THE REDUCTION OF Αa,β-UNSATURATED NITROALKENES USING SODIUM STANNITE
Varma, Rajender S.,Varma, Manju,Kabalka, George W.
, p. 6013 - 6014 (2007/10/02)
α,β-Unsaturated nitroalkenes are readily reduced by sodium stannite to ketoximes at room temperature.
