1036955-11-9

Basic information

• Product Name: (5-bromo-2-chloro-4-methoxyphenyl)(4-ethylphenyl)methanone
• Synonyms: (5-bromo-2-chloro-4-methoxyphenyl)(4-ethylphenyl)methanone
• CAS NO: 1036955-11-9
• Molecular Weight: 353.643
• Mol File: 1036955-11-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (5-bromo-2-chloro-4-methoxyphenyl)(4-ethylphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (5-bromo-2-chloro-4-methoxyphenyl)(4-ethylphenyl)methanone(1036955-11-9)
• EPA Substance Registry System: (5-bromo-2-chloro-4-methoxyphenyl)(4-ethylphenyl)methanone(1036955-11-9)

Safety Data

• Hazardous Substances Data: 1036955-11-9(Hazardous Substances Data)

Upstream product

• 174913-09-8 2-bromo-5-chloroanisole 
• 16331-45-6 p-ethylbenzoyl chloride 
• 13659-23-9 2-Bromo-5-chlorophenol 
• 74-88-4 methyl iodide 

Downstream Products

• 898538-44-8 1-bromo-4-chloro-5-(4-ethylbenzyl)-2-methoxybenzene 

Relevant articles and documents

Synthesis and biological evaluation of novel C-aryl D-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors

Novel C-aryl-d-glucofuranosides were synthesized and evaluated for their capacity to inhibit human sodium-dependent glucose co-transporter 2 (hSGLT2) and hSGLT1. Compound 21q demonstrated the best in vitro inhibitory activity against SGLT2 in this series (EC50 = 0.62 μM).

SPIROHETEROCYCLIC GLYCOSIDES AND METHODS OF USE

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.