103733-16-0Relevant articles and documents
Synthesis of β-lactams by condensation of titanium enolates of 2-pyridylthioesters with imines. Influence of the imine structure on the trans/cis stereoselectivity
Annunziata, Rita,Benaglia, Maurizio,Cinquini, Mauro,Cozzi, Franco,Ponzini, Francesco,Raimondi, Laura
, p. 2939 - 2948 (2007/10/02)
The condensation of the titanium enolates of C-2 alkyl substituted 2-pyridylthioesters with imines affords β-lactams in trans/cis ratios that largely depend on the structure of the C-imine residue. Bulky and non-chelating heteroatom-containing groups lead to the formation of trans β-lactams, while sterically non-requiring or chelating groups favour the formation of the cis-products. On the basis of NMR evidences a rationale is proposed to account for the observed stereoselectivity.
A Convenient Method for β-Lactam Formation from β-Amino Acids Using Phenyl Phosphorodichloridate Reagent
Palomo, Claudio,Aizpurua, Jesus M.,Urchegui, Raquel,Iturburu, Miren,Retana, Ana Ochoa de,Cuevas, Carmen
, p. 2244 - 2247 (2007/10/02)
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Asymmetric synthesis of β-lactams and the carbapenem antibiotic (+)-PS-5
Hart,Chih-Shone Lee,Pirkle,et al.
, p. 6054 - 6056 (2007/10/02)
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